Medicube PDRN Pink Peptide Serum with Salmon DNA

Overview

The hero ingredient is salmon DNA PDRN, and you use it as a targeted treatment step. With a strong 4.5 out of 5 from 959 ratings, it is a well-liked pick. It is one of the gentler options in the range, so it suits most skin types including sensitive skin.

The summary above follows how Medicube markets this product. We also read the published ingredient list line by line, and it tells a different story: what the ingredient order actually says.

At a glance

How the ratings break down

Amazon's own star distribution for this product, read on 2026-10-28. We show the one-star share too, because an average alone hides it.

8% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.

We cannot tell you what those reviewers said. Amazon.co.uk now requires an account to open the full review list, so the critical reviews are not readable from a public page. We would rather say that than guess.

What is salmon DNA PDRN?

PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.

Ingredients, as listed by Medicube

Taken from Medicube's own product page on 2026-08-05. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself. One more caveat for UK readers: Medicube has no separate UK site, so this list comes from its US product page. UK and EU ingredient lists can differ from the US one, so treat this as indicative until you have the pack in front of you.

Show the full ingredient list (39 ingredients)

WATER (AQUA), PROPANEDIOL, BUTYLENE GLYCOL, GLYCERIN, NIACINAMIDE, 1,2-HEXANEDIOL, SODIUM DNA, XANTHAN GUM, ETHYLHEXYLGLYCERIN, ADENOSINE, CITRIC ACID, SODIUM PHYTATE, CYANOCOBALAMIN, LEONTOPODIUM ALPINUM CALLUS CULTURE EXTRACT, FISH EXTRACT, LECITHIN, DIPOTASSIUM GLYCYRRHIZATE, SALMON EGG EXTRACT, ARGININE, CHOLESTEROL, CERAMIDE NP, COPPER TRIPEPTIDE-1, PEARL EXTRACT, SODIUM HYALURONATE, DIPEPTIDE-2, HYDROXYPROPYLTRIMONIUM HYALURONATE, OLIGOPEPTIDE-1, PALMITOYL PENTAPEPTIDE-4, TRIPEPTIDE-1, HYDROLYZED COLLAGEN, HYDROLYZED HYALURONIC ACID, SODIUM ACETYLATED HYALURONATE, HYALURONIC ACID, HYDROLYZED SODIUM HYALURONATE, SODIUM HYALURONATE CROSSPOLYMER, POTASSIUM HYALURONATE, HYDROLYZED CONCHIOLIN PROTEIN, PEARL POWDER, SUCCINOYL ATELOCOLLAGEN

What the ingredient order actually tells you

• Credit first: this is the rare PDRN product whose list backs the name. Salmon DNA sits seventh of 39, about as high as we have seen it placed anywhere in this range.
• The support cast is strong too: niacinamide fifth, adenosine tenth, ceramide 21st, then hyaluronic entries from 24th onward.
• The peptide half of the name is softer. The peptide entries run from 22nd to 29th, respectable but mid-table.
• No fragrance and no drying alcohol appear on the list.

Our read

If you have decided you want to try PDRN, this is the honest way in: the ingredient is genuinely near the top rather than sprinkled on for the label. What topical PDRN actually does is still a young evidence area, and no ingredient list settles that. As a light, unfragranced hydrator with niacinamide and adenosine up front, it stands on its own regardless.

Who should skip this

• You want peptides to lead. They start at 22nd of 39, behind the hydration core.
• Your skin wants a rich, cushioning serum. This is built ultra light on purpose.
• You need established evidence before paying for a trend ingredient. PDRN's topical case is early days, and that is not the list's fault, it is the field's.

A note on how we read that list. Ingredient lists run in descending order of concentration, but only for ingredients above 1%. Below that, the order is up to the manufacturer, so a low position tells you something is present at a low level, not exactly how much. We do not guess at percentages. FDA labeling guide.

What the listing says

Medicube's own description of this product, as published on its Amazon.co.uk listing. It is marketing copy, not our assessment, and we have not verified the claims in it.

• medicube PDRN Pink Peptide Serum with Salmon DNA | Ultra Light Hydrating Serum with Hyaluronic Acid | Fast-Absorbing Glow Care for Skin Clarity | Korean Skincare, 110ml

Full listing title: medicube PDRN Pink Peptide Serum with Salmon DNA | Ultra Light Hydrating Serum with Hyaluronic Acid | Fast-Absorbing Glow Care for Skin Clarity | Korean Skincare, 110ml

Frequently asked questions

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