Medicube Salmon DNA PDRN Pink Peptide Serum vs Zero Exosome: which should you buy?
PDRN Pink against the stronger Zero Exosome Shot: everyday glow serum or higher-intensity treatment.
medicube medicube Salmon DNA PDRN Pink Peptide Serum, Pink
4.6(23,534) £13.78£16.90-18% Check price on Amazon →
medicube medicube Zero Exosome Shot 7,500 PPM Spicule Facial
4.5(5,788) £17.90£19.50-8% Check price on Amazon →The short answer
Buy the PDRN Pink serum if you want a gentle, daily glow serum that suits almost everyone.
Buy the Zero Exosome Shot if you tolerate actives and want a stronger, spicule-boosted treatment a few times a week.
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Side by side
| medicube Salmon DNA PDRN Pink Peptide | medicube Zero Exosome Shot 7,500 PPM | |
|---|---|---|
| Price | £13.78£16.90-18% See on Amazon → | £17.90£19.50-8% See on Amazon → |
| Rating | ★★★★★ 4.6 | ★★★★★ 4.5 |
| Review count | 23,534 | 5,788 |
| Amazon best-seller rank | #3 in Face Serums | #38 in Face Serums |
| Amazon purchases | 20K+ bought | 700+ bought |
| Key active | salmon DNA PDRN | exosomes |
| Format | serum | concentrated serum |
| Size | 1.01 fl.oz | 30ml |
| Routine step | treat | treat |
| Best for | glow | congestion |
| Sensitive-skin friendly | Listing flags no strong actives | Contains actives, patch test |
| Highlights |
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Our verdict
Both come from Medicube's regeneration story, but they sit at different intensities. The Salmon DNA PDRN Pink serum is the gentle, everyday hero (24k ratings at 4.6) built around glow, bounce and barrier comfort, safe to use daily and easy to layer. The Zero Exosome Shot is the concentrated one: a 7,500 PPM spicule serum that uses tiny spicules to boost absorption and give a more intensive, treatment-style hit, which some skin loves and some finds too much too often. Think of PDRN Pink as your daily driver and the Exosome Shot as a periodic booster. If you want one simple serum you can slap on every night without thinking, PDRN Pink is the safer, more forgiving choice. If you already tolerate actives well and want a stronger, more targeted session a couple of times a week, the Exosome Shot delivers more punch, just introduce it slowly and watch how your skin responds.
Which one is for you?
- Buy the PDRN Pink serum if you want a gentle, daily glow serum that suits almost everyone. Read our full look at the medicube Salmon DNA PDRN Pink Peptide →
- Buy the Zero Exosome Shot if you tolerate actives and want a stronger, spicule-boosted treatment a few times a week. Read our full look at the medicube Zero Exosome Shot 7,500 PPM →
Frequently asked questions
What is the difference between the medicube Salmon DNA PDRN Pink Peptide and the medicube Zero Exosome Shot 7,500 PPM?
PDRN Pink against the stronger Zero Exosome Shot: everyday glow serum or higher-intensity treatment.
Which is better, the medicube Salmon DNA PDRN Pink Peptide or the medicube Zero Exosome Shot 7,500 PPM?
Neither is simply better; it depends on your skin and goal. Buy the PDRN Pink serum if you want a gentle, daily glow serum that suits almost everyone. Buy the Zero Exosome Shot if you tolerate actives and want a stronger, spicule-boosted treatment a few times a week.
Can I use the medicube Salmon DNA PDRN Pink Peptide and the medicube Zero Exosome Shot 7,500 PPM together?
Often yes. If they sit at different routine steps you can layer them lightest to heaviest, and if they do the same job you would usually pick one. Introduce new actives one at a time and patch test first.
Where these claims come from
- Star ratings and review counts: Amazon.co.uk's own figures for each listing, read on 2026-10-01.
- Prices and stock: read from each Amazon.co.uk listing, read on 2026-10-01.
- Best Sellers Rank and "bought in past month" badges: Amazon.co.uk's own figures, shown on the product page, read on 2026-10-01.
- Ingredient list as published by the manufacturer · medicube.us
- Ingredient list as published by the manufacturer
We have not tested either product. Everything above is read from the listings and the manufacturer, with the dates shown, plus our own reading of what the two are for. Ratings are Amazon customers' scores, not ours.
Amazon.co.uk figures, not ours: prices read on 2026-10-01; star ratings and review counts read on 2026-10-01. Prices and ratings change; these are dated snapshots.
Prices move around, so always confirm on Amazon before deciding. Browse more options in PDRN & Salmon DNA or browse the whole range.