Medicube Rosemary PDRN Clarifying Shampoo

Overview

Medicube markets this on salmon DNA PDRN, and you use it as a targeted treatment step. With a strong 4.4 out of 5 from 478 ratings, it is a well-liked pick. Its Amazon listing does not flag strong actives, which is a filter on listing text rather than a safety assessment.

The summary above follows how Medicube markets this product. We also read the published ingredient list line by line, and it tells a different story: what the ingredient order actually says.

At a glance

What buyers actually say

We read a sample of the Amazon reviews for this product and describe the pattern in our own words. It is a sample, not a survey of all 770 ratings, and we do not reproduce customer reviews.

Our sample is small, and skews towards women with fine or thinning hair, several of them post-menopausal. What they report consistently is a clean, non-flaky scalp, a cooling tingle during washing, and hair left soft and lifted at the root rather than weighed down. Two mention new growth or added volume after a few weeks, though both had made other changes at the same time. The reservations are specific rather than sweeping: the medicinal, vapour-rub sort of scent divides opinion, one reviewer hoped it would curb greasiness and it did not, and the matching conditioner was judged weak. Seven percent of all ratings sit at one star, and none appear here.

How the ratings break down

Amazon's own star distribution for this product, read on 2026-10-01. We show the one-star share too, because an average alone hides it.

9% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.

We cannot tell you what those reviewers said. Amazon.co.uk now requires an account to open the full review list, so the critical reviews are not readable from a public page. We would rather say that than guess.

What is salmon DNA PDRN?

PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.

Ingredients, as listed by Medicube

Taken from Medicube's own product page on 2026-08-05. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself. One more caveat for UK readers: Medicube has no separate UK site, so this list comes from its US product page. UK and EU ingredient lists can differ from the US one, so treat this as indicative until you have the pack in front of you.

Show the full ingredient list (107 ingredients)

Water (Aqua), Sodium Cocoyl Isethionate, Disodium Laureth Sulfosuccinate, Glycerin, Cocamidopropyl Hydroxysultaine, Lauryl Betaine, Glyceryl Stearate, Sodium Lauroyl Methylaminopropionate, Menthol, Trihydroxystearin, Sodium Chloride, Fragrance (Parfum), Sodium Benzoate, Cetyl Alcohol, Dicaprylyl Ether, Polyquaternium-10, Panthenol, Salicylic Acid, Citric Acid, Caprylyl Glycol, Niacinamide, Tetrasodium EDTA, Zea Mays (Corn) Starch, Mannitol, Microcrystalline Cellulose, Linalool, Carthamus Tinctorius (Safflower) Flower Extract, Dextrin, Gardenia Florida Fruit Extract, Chromium Oxide Greens, Ultramarines, Chromium Hydroxide Green, Tocopheryl Acetate, Hydrogenated Lecithin, Tocopherol, Butylene Glycol, Sodium Citrate, Caffeine, Arginine, Dipropylene Glycol, Gluconolactone, Menthyl Lactate, PPG-14 Butyl Ether, Ricinus Communis (Castor) Seed Oil, Glycolic Acid, Saccharide Isomerate, Sodium C14-16 Olefin Sulfonate, 1,2-Hexanediol, Hydrolyzed Pea Protein, Hydrolyzed Vegetable Protein, Caprylic/Capric Triglyceride, Raphanus Sativus (Radish) Seed Extract, Sodium Palmitoyl Sarcosinate, Octyldodecyl Oleate, Octyldodecanol, Sparassis Crispa Extract, Streptococcus Thermophilus Ferment, Hydrolyzed Collagen, Hydrolyzed Corn Protein, Hydrolyzed Extensin, Hydrolyzed Potato Protein, Hydrolyzed Rice Protein, Hydrolyzed Soy Protein, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Prunus Amygdalus Dulcis (Sweet Almond) Extract, Potassium Sorbate, Sodium DNA (2.5 ppb), Magnolia Obovata Bark Extract, Hydrolyzed Keratin, Disodium EDTA, Rosmarinus Officinalis (Rosemary) Leaf Extract (0.25 ppb), Biotin, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-11, sh-Polypeptide-22, sh-Polypeptide-3, sh-Polypeptide-9, Alanine, Asparagine, Aspartic Acid, Dimethylsilanol Hyaluronate, Glucose, Glutamic Acid, Glutamine, Glycine, Histidine, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Isoleucine, Leucine, Lysine, Mentha Piperita (Peppermint) Leaf Extract, Methionine, Phenylalanine, Proline, Serine, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Threonine, Tryptophan, Tyrosine, Valine

What the ingredient order actually tells you

• At 107 entries this is the longest list in the range, and the top of it tells you what kind of product this is: menthol ninth, fragrance 12th, panthenol 17th, salicylic acid 18th. A tingly, scented clarifying shampoo with the salicylic acid placed where it can actually matter.
• The wash base leans mild: sodium cocoyl isethionate second and a sulfosuccinate third, rather than the harsher sulphates.
• The skincare celebrity section is a long walk to the back: caffeine 38th, collagen 58th, salmon DNA at 67th of 107, peptides from 73rd, hyaluronic entries from 83rd.
• Rosemary is present under its Latin name, Rosmarinus Officinalis, at 71st of 107.

Our read

As a clarifying shampoo the working half of the list is competently built: milder-leaning surfactants, menthol for the fresh scalp feel, salicylic acid at 18th. The PDRN and peptide branding sits far down the list at 67th and beyond, and in a product you rinse straight out it was never going to be more than branding. Buy the shampoo, not the biotech.

Who should skip this

• Fragrance or menthol on the scalp sets you off. They sit 12th and ninth, right up front.
• You are paying a premium for salmon DNA. At 67th of 107, in a rinse-off, it is a sticker.
• You wanted a rosemary-oil scalp routine. Rosemary leaf extract is on the list, but at 71st of 107 in a product you rinse off.

A note on how we read that list. Ingredient lists run in descending order of concentration, but only for ingredients above 1%. Below that, the order is up to the manufacturer, so a low position tells you something is present at a low level, not exactly how much. We do not guess at percentages. FDA labeling guide.

Frequently asked questions

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