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PDRN & Salmon DNA · Head to head

Medicube PDRN Toner Salmon DNA PDRN CICA vs NAD EGF Firming: which should you buy?

An all-skin-types PDRN toner against a firming NAD EGF serum aimed at pores and the look of ageing.

The short answer

Choose the medicube PDRN Toner Salmon DNA PDRN

if you want a gentle daily hydrating step, especially with dry or sensitive skin, backed by the largest review base here.

Choose the medicube NAD EGF Firming Serum

if you have oily or combination skin and want a treatment step focused on pores, elasticity and lines.

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Side by side

medicube PDRN Toner Salmon DNA PDRNmedicube NAD EGF Firming Serum
Price£14.20£15.60-9% See on Amazon →£16.90£18.90-11% See on Amazon →
Rating★★★★★ 4.7★★★★★ 4.5
Review count4,8022,940
Amazon best-seller rank#11 in Face Astringents & Toners#8 in Face Serums
Amazon purchases1K+ bought10K+ bought
Key activesalmon DNA PDRNNAD and EGF
Formattonerserum
Size8.45 fl. Oz1.01 fl.oz
Routine steptonetreat
Best forglowfirmness
Sensitive-skin friendlyListing flags no strong activesListing flags no strong actives
Highlights
  • Glow Booster Toner: Glow Boosting Toner with Salmon DNA PDRN that helps improve skin texture, while enhancing …
  • Salmon DNA PDRN: Salmon DNA PDRN stimulates skin renewal and repair, giving your skin a clearer, more luminous…
  • Strengthens the Skin Barrier & Enhances Radiance: Reinforces the skin barrier to prevent moisture loss while g…
  • [RECHARGE & FIRM] Powered by next-generation ingredients including NAD+ and EGF to improve the appearance of w…
  • [VISIBLE FIRMING RESULTS] Helps improve the appearance of wrinkles and skin firmness across key areas includin…
  • [NAD+, EGF, COLLAGEN FIRMING COMPLEX] Formulated with EGF peptide, NAD+, and Collagen to help nourish and revi…

Our verdict

These do different jobs, and the skin type lists tell you which one is for you before the ratings do. The PDRN CICA Soothing Toner is an 8.45 fl oz toning step with PDRN, niacinamide and peptides, listed for all five skin types including sensitive, and focused on glow and hydration. It rates slightly higher and has the larger review base, so it is the deeper evidence base here. The NAD EGF Firming Serum sits marginally lower on a smaller but fast-growing review count, and it is aimed at oily, combination and normal skin only, targeting pores, firmness and the appearance of ageing. The toner is also the cheaper of the two. If your skin is dry or sensitive, the serum is not listed for you and the toner is the straightforward pick. If you are oily or combination and your concern is texture and pores rather than plain hydration, the serum is the more specific tool. Many people would use both.

Which one is for you?

Frequently asked questions

What is the difference between the medicube PDRN Toner Salmon DNA PDRN and the medicube NAD EGF Firming Serum?

An all-skin-types PDRN toner against a firming NAD EGF serum aimed at pores and the look of ageing.

Which is better, the medicube PDRN Toner Salmon DNA PDRN or the medicube NAD EGF Firming Serum?

Neither is simply better; it depends on your skin and goal. Choose the PDRN CICA Soothing Toner if you want a gentle daily hydrating step, especially with dry or sensitive skin, backed by the largest review base here. Choose the NAD EGF Firming Serum if you have oily or combination skin and want a treatment step focused on pores, elasticity and lines.

Can I use the medicube PDRN Toner Salmon DNA PDRN and the medicube NAD EGF Firming Serum together?

Often yes. If they sit at different routine steps you can layer them lightest to heaviest, and if they do the same job you would usually pick one. Introduce new actives one at a time and patch test first.

Where these claims come from

  • Star ratings and review counts: Amazon.co.uk's own figures for each listing, read on 2026-10-01.
  • Prices and stock: read from each Amazon.co.uk listing, read on 2026-10-01.
  • Best Sellers Rank and "bought in past month" badges: Amazon.co.uk's own figures, shown on the product page, read on 2026-10-01.

We have not tested either product. Everything above is read from the listings and the manufacturer, with the dates shown, plus our own reading of what the two are for. Ratings are Amazon customers' scores, not ours.

Amazon.co.uk figures, not ours: prices read on 2026-10-01; star ratings and review counts read on 2026-10-01. Prices and ratings change; these are dated snapshots.

Prices move around, so always confirm on Amazon before deciding. Browse more options in PDRN & Salmon DNA or browse the whole range.