Overview
The hero ingredient is salmon DNA PDRN, and you use it as your daily moisturizer. With an excellent 4.6 out of 5 from over 2k ratings, it is one of the best-reviewed pdrn & salmon dna in the range. It is one of the gentler options in the range, so it suits most skin types including sensitive skin.
Pros
- Excellent 4.6/5 rating from 2k shoppers
- Built around salmon DNA PDRN, a genuinely on-trend active
- Affordable for what it is, undercutting many Western equivalents
- Gentle enough for daily use on most skin types
Cons
- As a food-and-cosmetic product, results vary from person to person
- Sold mainly through Amazon, so stock and price can move
At a glance
| Type | PDRN & Salmon DNA |
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| Key ingredient | salmon DNA PDRN |
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| Format | moisturizer |
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| Size | 1.69 fl. oz |
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| Routine step | Moisturiser |
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| Best for skin type | Oily, Dry, Sensitive, Combination, Normal |
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| Sensitive-skin friendly | Yes, one of the gentler picks |
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| Rating | 4.6 / 5 from 1,735 ratings |
What buyers actually say
We read a sample of the Amazon reviews for this product and describe the pattern in our own words. It is a sample, not a survey of all 1,735 ratings, and we do not reproduce customer reviews.
Reviewers in our sample describe a light, fast-absorbing cream rather than a rich one, and the recurring praise is that it hydrates without leaving a greasy film. Several mention a glassy or plumped look the morning after, and that a small amount covers the whole face, which softens the price complaint for some. Opinion on scent splits mildly, with some noticing none and others enjoying it. The complaints are modest: one reviewer found it pilled under makeup and moved it to evenings, another wanted a larger tube, and the single two-star voice in the sample felt it was a decent moisturiser but not special enough for the money.
Praised for
- Hydrates without feeling greasy or sticky
- Absorbs fast, glassy plumped finish
- A little goes a long way
- Feels gentle on the skin
Criticised for
- Can pill under makeup, better used at night
- Tube feels small for the price
- One reviewer thought it was an ordinary moisturiser at a premium price
How the ratings break down
Amazon's own star distribution for this product, read on 2026-08-02. We show the one-star share too, because an average alone hides it.
5 star 79%
4 star 14%
3 star 4%
2 star 1%
1 star 2%
What is salmon DNA PDRN?
PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.
Key features
- Blemish Relief & Skin Healing: Powered by Salmon DNA PDRN, this cream deeply nourishes and promotes the recovery of damaged or blemished skin, reducing the appearance of marks and uneven skin tone.
- Hydrating & Firming with Hyaluronic Acid: Boosts moisture levels and enhances skin elasticity, helping your skin feel smoother and more supple while providing long-lasting hydration.
- Korean Glass Glow Effect: Achieve glowing, radiant skin with a formula that improves skin texture and supports a healthier, clearer complexion.
- Lightweight, Non-Greasy Relief Texture: Absorbs easily into the skin, leaving a silky, comforted finish with no sticky residue - ideal for daily relief-focused use.
- Pore Care & Skin Barrier Relief Support: Strengthens your skin’s natural barrier, helping to reduce visible pores and improve a smooth, even skin tone.
Frequently asked questions
Is the medicube Salmon DNA PDRN Pink Hyaluronic Moisturizing good for sensitive skin?
Yes, it is one of the gentler options in the range and suits most skin types, including sensitive skin. As always, patch test first.
How do you use the medicube Salmon DNA PDRN Pink Hyaluronic Moisturizing?
Use it as the last step of your routine (before sunscreen in the morning). Follow the directions on the pack, and always finish your morning routine with sunscreen.
Is the medicube Salmon DNA PDRN Pink Hyaluronic Moisturizing worth it?
For the price, it is an easy recommendation: 4.6 out of 5 from a large number of shoppers, doing a clear job in the routine. Results vary from person to person, so manage expectations.
Check price on Amazon →